PCBD1 Polyclonal Antibody | E-AB-19099

PCBD1 Polyclonal Antibody | E-AB-19099 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 4 alpha hydroxy tetrahydropterin dehydratase, 4-alpha-hydroxy-tetrahydropterin dehydratase, 6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1), 6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha, DCoH, Dimerization cofactor of hepatic nuclear factor 1 alpha, Dimerization cofactor of hepatocyte nuclear factor 1 alpha, Dimerization cofactor of hepatocyte nuclear factor 1-alpha, Dimerization cofactor of HNF1, Dimerizing cofactor for HNF1, PCBD 1, PCBD, PCBD1, PCD, Phenylalanine hydroxylase stimulating protein, Phenylalanine hydroxylase-stimulating protein, PHS, PHS, Pterin 4 alpha carbinolamine dehydratase, Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1), Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha, Pterin carbinolamine dehydratase, Pterin-4-alpha-carbinolamine dehydratase

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction

Background: This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.

Concentration: 1.02 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human PCBD1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 12 kDa

Molecular Weight(Observed): Refer to figures