PCCA Antibody | 23-871

PCCA Antibody | 23-871 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 449-728 of human PCCA (NP_000273.2) .

Research Area: Cancer, Signal Transduction

Tested Application: WB

Application: WB: 1:1000 - 1:3000

Specificiy: N/A

Positive Control 1: Mouse pancreas

Positive Control 2: Mouse liver

Positive Control 3: Mouse brain

Positive Control 4: Mouse kidney

Positive Control 5: Rat kidney

Positive Control 6: N/A

Molecular Weight: Observed: 80kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: PCCA,

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.