PD-123319 ditrifluoroacetate | 9640

PD-123319 is a potent, selective, non-peptide angiotensin AT2 receptor antagonist (IC₅₀ values are 34 and 210 nM in rat adrenal tissue and brain respectively). It has been used to selectively examine the specific roles for AT1R and AT2R in hypertensive and other vascular research-related models.

PD-123319 is a potent, selective, non-peptide angiotensin AT2 receptor antagonist (IC₅₀ values are 34 and 210 nM in rat adrenal tissue and brain respectively). It has been used to selectively examine the specific roles for AT1R and AT2R in hypertensive and other vascular research-related models.

9640 | PD-123319 ditrifluoroacetate DataSheet

Alternate Name/Synonyms: 1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid ditrifluoroacetate

Appearance: Off-white solid

Formulation: N/A

CAS Number: 136676-91-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₁H₃₂N₄O₃.2CF₃CO₂H

Molecular Weight: 736.67

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: H₂O (>70 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, selective, non-peptide angiotensin AT2 receptor antagonist

MDL Number: MFCD11046022

PubChem CID: N/A

SMILES: O=C(C1CC2=C(N=CN2CC3=CC=C(N(C)C)C(C)=C3)CN1C(C(C4=CC=CC=C4)C5=CC=CC=C5)=O)O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

InChi: InChI=1S/C31H32N4O3.2C2HF3O2/c1-21-16-22(14-15-26(21)33(2)3)18-34-20-32-25-19-35(28(31(37)38)17-27(25)34)30(36)29(23-10-6-4-7-11-23)24-12-8-5-9-13-24;2*3-2(4,5)1(6)7/h4-16,20,28-29H,17-19H2,1-3H3,(H,37,38);2*(H,6,7)

InChi Key: GPKQIEZLHVGJQH-UHFFFAOYSA-N