Description
Cell-permeable. A selective, non-competitive Calpain inhibitor (Ki = 210 nM and 370 nM for Calpain-1 and Calpain-2, respectively). Interacts with the calcium-binding domain of calpain.
PD 150, 606 is a selective, non-competitive Calpain inhibitor (Ki = 210 nM and 370 nM for Calpain-1 and Calpain-2, respectively). Interacts with the calcium-binding domain of calpain.
Alternate Name/Synonyms: 3-(4-Iodophenyl)-2-mercapto-(Z)-2-propenoic acid
Appearance: Off-white solid
Formulation: N/A
CAS Number: 179528-45-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₉H₇IO₂S
Molecular Weight: 306.12
Cell-Permeable?: Yes
Purity: ≥98% by NMR
Solubilities: DMSO (10 mg/ml) or EtOH (1 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective, non-competitive Calpain inhibitor
MDL Number: MFCD00949076
PubChem CID: 9839500
SMILES: C1=CC(=CC=C1C=C(C(=O)O)S)I
InChi: InChI=1S/C9H7IO2S/c10-7-3-1-6(2-4-7)5-8(13)9(11)12/h1-5,13H,(H,11, 12)/b8-5-
InChi Key: DJCVSFWGKYHMKH-YVMONPNESA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |