PDCD6IP polyclonal Antibody | BS70704

PDCD6IP polyclonal Antibody | BS70704 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB,IHC,IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: Alix, a phylogenetically conserved cytosolic scaffold protein, contains an N-terminal Bro1 domain, a coiled-coil region and a C-terminal proline-rich domain (1,2) . Originally identified as an ALG-2 (apoptosis-linked gene 2) -interacting protein involved in programmed cell death (3,4), Alix also regulates many other cellular processes, such as endocytic membrane trafficking and cell adhesion through interactions with ESCRT (endosomal sorting complex required for transport) proteins, endophilins, and CIN85 (Cbl-interacting protein of 85 kDa) (5,6) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PDCD6IP polyclonal Antibody detects endogenous levels of PDCD6IP protein.

Molecular Weight: ~ 105 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Programmed cell death 6-interacting protein; PDCD6-interacting protein; ALG-2-interacting protein 1; ALG-2-interacting protein X Hp95; AIP1; ALIX; KIAA1375

Immunogen: Recombinant Protein of human PDCD6IP.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: ATP-Dependent Chromatin Remodeling Complexes,DNA Methylation,