PDCL2 Antibody | 7887

PDCL2 Antibody | 7887 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: PDCL2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human PDCL2.
The immunogen is located within the last 50 amino acids of PDCL2.

Research Area: Signal Transduction

Tested Application: E, WB

Application: PDCL2 antibody can be used for detection of PDCL2 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Specificiy: PDCL2 antibody is human, mouse and rat reactive. PDCL2 antibody is predicted to not cross-react with other members of the PDCL protein family.

Positive Control 1: Cat. No. 1464 - Rat Liver Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 27 kDa
Observed: 25 kDa

Validation: N/A

Isoform: N/A

Purification: PDCL2 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PDCL2 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: PDCL2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: PDCL2 Antibody: GCPHLP, Phosducin-like protein 2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling (1, 2) . PDCL2 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain (3) . PDCL2 has been shown to interact with the chaperonin CCT and is essential for cytoskeletal protein function and cell cycle progression (4) .