PDE2A Antibody (C-Term) [APR33432G]

PDE2A Antibody (C-Term) [APR33432G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This PDE2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 780-810 amino acids of mouse PDE2A.

Cellular Localisation: [Isoform PDE2A3]: Cell membrane; Lipid- anchor [Isoform PDE2A1]: Cytoplasm

Molecular Weight: 105717

Clone: Polyclonal

Gene Name: PDE2A

Gene ID: 5138

Function: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line) (PubMed:24705027) .

Summary: Tissue Location: Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: cGMP-dependent 3', 5'-cyclic phosphodiesterase, 3.1.4.17, Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE, PDE2A