LBD
PDE2A Antibody (C-Term) [APR33432G]
- SKU:
- LBD-APR33432G
- Availability:
- Usually ships in 5 working days
Description
PDE2A Antibody (C-Term) [APR33432G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M
Specificity: This PDE2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 780-810 amino acids of mouse PDE2A.
Cellular Localisation: [Isoform PDE2A3]: Cell membrane; Lipid- anchor [Isoform PDE2A1]: Cytoplasm
Molecular Weight: 105717
Clone: Polyclonal
Gene Name: PDE2A
Gene ID: 5138
Function: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line) (PubMed:24705027) .
Summary: Tissue Location: Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: cGMP-dependent 3', 5'-cyclic phosphodiesterase, 3.1.4.17, Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE, PDE2A