PDGFR-β Polyclonal Antibody | ABP0113

PDGFR-β Polyclonal Antibody | ABP0113 | Gentaur UK, US & Europe Distribution

Immunogen: Synthesized peptide derived from human PDGFR-β around the non-phosphorylation site of Y751

Product Category: Protein

Application: Protein General Reagents

Product Type: Selected Primary Antibodies

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB, IF, IHC-P, ELISA

Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), IHC-P (1:100-1:300), ELISA (1:40000) . Not yet tested in other applications.

Clonality: Polyclonal

Isotype: Rabbit IgG

Formulation: Liquid solution

Kit Component: N/A

Concentration: 1 mg/ml

Storage Buffer: PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Shipping Condition: Gel pack with blue ice.

Background: PDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses PDGFRB to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Alternative Names: PDGFRB; PDGFR; PDGFR1; Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri

Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.