PDGFRB Polyclonal Antibody | E-AB-32531

PDGFRB Polyclonal Antibody | E-AB-32531 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Beta platelet derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD 140B, CD140 antigen-like family member B, CD140b, CD140b antigen, IBGC4, IMF1, JTK12, OTTHUMP00000160528, PDGF R beta, PDGF-R-beta, PDGFR 1, PDGFR, PDGFR beta, PDGFR1, PDGFRB, PGFRB, Platelet derived growth factor receptor 1, Platelet derived growth factor receptor beta, Platelet derived growth factor receptor beta polypeptide

Application: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Signal Transduction

Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human PDGFR-β around the non-phosphorylation site of Tyr751.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 124 kDa

Molecular Weight(Observed): 124 kDa