Description
PDX1 polyclonal Antibody | BS91049 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Application: WB IHC ICC/IF
Application Range: IHC:1:50-1:200 ICC/IF:1:50-1:200 WB:1:500
Background: Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: PDX1 polyclonal Antibody detects endogenous levels of PDX1 protein.
Molecular Weight: N/A
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: PDX-1, GSF, IPF-1, IUF-1, IDX-1, STF-1, Glucose sensitive factor, Glucose-sensitive factor, GSF, IDX 1, IDX-1, IDX1, Insulin promoter factor 1, Insulin promoter factor 1 homeodomain transcription factor, Insulin upstream factor 1, IPF 1, IPF-1, IPF1, Islet/duodenum homeobox 1, Islet/duodenum homeobox-1, IUF 1, IUF-1, IUF1, MODY4, Pancreas/duodenum homeobox 1, Pancreas/duodenum homeobox protein 1, pancreatic and duodenal homeobox P, PDX 1, PDX-1, PDX1, PDX1, Somatostatin transactivating factor 1, Somatostatin-transactivating factor 1, STF 1, STF-1, STF1,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: