PDYN polyclonal Antibody | BS7886

PDYN polyclonal Antibody | BS7886 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200

Background: The Proenkephalin precursor proteins are secreted proteins belonging to the opioid neuropeptide precursor family. The Proenkephalin proteins are proteolytically processed to form active secreted opioid peptides, which function as ligands for the ˚-type of opioid receptor. The Proenkephalin A precursor contains Synenkephalin, Leu-enkephalin and Met-enkephalin processed active peptides, while the Proenkephalin B precursor contains β-neoendorphin, Dynorphin, Leumorphin, Leu-enkephalin and rimorphin processed active peptides. β-endorphin and Met-enkephalin are endogenous opiates, while ACTH is crucial for adrenal gland stimulation to release cortisol. MSH increases melanin production in melanocytes, which leads to an increase in skin pigmentation. Leumorphin may be important in apoptosis prevention by being involved in the MAP kinase and PI 3-kinase pathways.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PDYN polyclonal Antibody detects endogenous levels of PDYN protein.

Molecular Weight: ~ 28 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ADCA; Alpha neoendorphin; Beta neoendorphin; Beta-neoendorphin-dynorphin; Big Dyn; Big dynorphin; Dyn; Dyn-A17; Dyn-B; Dynorphin A; Dynorphin A (1-13) ; Dynorphin A (1-17) ; Dynorphin A (1-8) ; Dynorphin B; Dynorphin B (1-13) ; Dynorphin B-29; Enkephalin B; Leu enkephalin; Leumorphin; Neoendorphin dynorphin enkephalin prepropeptide; PDYN; PDYN_HUMAN; PENKB; Preprodynorphin; Preproenkephalin B; Prodynorphin; Proenkephalin B; Rimorphin; SCA23;

Immunogen: Recombinant full length Human PDYN.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: