Gentaur

Peripherin Antibody | Gentaur

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SKU:: 147-AP06284PU-N-GEN-GEN
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Description
Additional Information

Description

Peripherin Antibody

Biological source

rabbit

Quality Level

100

Conjugate

unconjugated

Antibody form

affinity isolated antibody

Antibody product type

primary antibodies

Clone

polyclonal

Form

buffered aqueous solution

Mol wt

antigen 53 kDa

Species reactivity

human, rat

Concentration

~1 mg/mL

Anti-Peripherin antibody detects endogenous levels of total Peripherin protein.

The PRPH (peripherin) gene is mapped to human chromosome 12q13.12. This gene codes for a 57 kDa intermediate filament protein. Peripherin is predominantly expressed in the peripheral neurons.

Peripherin is known to be associated with the mechanism of organelle transport, function and positioning. It also forms an important part of the cytoskeleton. Mutation in PRPH (peripherin) is observed in amyotrophic lateral sclerosis. Peripherin participates in the elongation of motor axons. Upregulation of PRPH is noticed in neuronal injury.

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