Perphenazine | B3115

Perphenazine is a dopamine receptor antagonist. It binds to Dopamine receptors D₂, D₃ and D₄ with Ki values of 0.56 nM, 0.43 nM and 28.5 nM respectively. It also binds to serotonin receptors 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6 and 5-HT7 with Ki values of 421 nM, 5.6 nM, 132 nM, 17 and 23 nM respectively. It is used as an antipsychotic drug.

Perphenazine is a dopamine receptor antagonist. It binds to Dopamine receptors D₂, D₃ and D₄ with Ki values of 0.56 nM, 0.43 nM and 28.5 nM respectively. It also binds to serotonin receptors 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6 and 5-HT7 with Ki values of 421 nM, 5.6 nM, 132 nM, 17 and 23 nM respectively. It is used as an antipsychotic drug.

B3115 | Perphenazine DataSheet

Alternate Name/Synonyms: Trilafon; Etaperazine; Chlorpiprazine; 2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol; 2-Chloro-10-3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl phenothiazine

Appearance: White to off-white powder

Formulation:

CAS Number: 58-39-9

Structure Available?: TRUE

Peptide sequence:

Salt Form: FALSE

Molecular Formula: C₂₁H₂₆ClN₃OS

Molecular Weight: 403.97

Cell-Permeable?: True

Purity: ≥ 97%

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A dopamine receptor antagonist

MDL Number: MFCD00056798

PubChem CID: 4748

SMILES: C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO

InChi: InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2

InChi Key: RGCVKNLCSQQDEP-UHFFFAOYSA-N