PEX2 polyclonal Antibody | BS3900

PEX2 polyclonal Antibody | BS3900 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Peroxisomes are involved in numerous catabolic and anabolic pathways, including β-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. Peroxins are proteins involved in peroxisome biogenesis. The peroxisome biogenesis factor Peroxin 2 (also designated Pex2) is an integral membrane protein of peroxisomes. Defects in the PXMP3 gene encoding Peroxin 2 are the cause of Zellweger syndrome-1 (ZWS-1), an autosomal recessive disorder due to defective import mechanisms for peroxisomal matrix enzymes. ZWS-1 is a severe form of the peroxisome-biogenesis disorders, a group of genetically heterogeneous, lethal diseases that are characterized by neuronal, hepatic and renal abnormalities, mental retardation and, in their most severe form,death within the first year of life.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PEX2 polyclonal Antibody detects endogenous levels of PEX2 protein.

Molecular Weight: ~34kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Peroxisome biogenesis factor 2; 35 kDa peroxisomal membrane protein; Peroxin-2; Peroxisomal membrane protein 3; Peroxisome assembly factor 1; PAF-1; RING finger protein 72; PEX2; PAF1; PMP3; PMP35; PXMP3; RNF72

Immunogen: Synthetic peptide, corresponding to Human PEX2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Histone Lysine Methylation Pathway,