PF-06291874 | B2001

PF-06291874 is a glucagon receptor antagonist potentially useful for patients with type 2 diabetes mellitus.

PF-06291874 is a glucagon receptor antagonist potentially useful for patients with type 2 diabetes mellitus.

B2001 | PF-06291874 DataSheet

Alternate Name/Synonyms: N-[4-[(1S)-1-[3,5-Dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy]butyl]benzoyl]—alanine; PF6291874.

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1393124-08-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₂₈F₃N₃O₄

Molecular Weight: 503.52

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A glucagon receptor antagonist

MDL Number: N/A

PubChem CID: 60151939

SMILES: CCCC(C1=CC=C(C=C1)C(=O)NCCC(=O)O)OC2=CC(=C(C(=C2)C)N3C=C(C=N3)C(F)(F)F)C

InChi: InChI=1S/C26H28F3N3O4/c1-4-5-22(18-6-8-19(9-7-18)25(35)30-11-10-23(33)34)36-21-12-16(2)24(17(3)13-21)32-15-20(14-31-32)26(27,28)29/h6-9,12-15,22H,4-5,10-11H2,1-3H3,(H,30,35)(H,33,34)/t22-/m0/s1

InChi Key: IBDYYOQKQCCSDP-QFIPXVFZSA-N