PF-4989216 | B1659

PF-4989216 is a novel potent and selective PI3K inhibitor. PF-4989216 inhibits PI3Kalpha (Ki=0.6 nM) and mTOR (Ki=1440 nM).

PF-4989216 is a novel potent and selective PI3K inhibitor. PF-4989216 inhibits PI3Kalpha (Ki=0.6 nM) and mTOR (Ki=1440 nM).

B1659 | PF-4989216 DataSheet

Alternate Name/Synonyms: PF-4989216, PF4989216; PF 4989216; 4-(4-cyano-2-fluorophenyl)-2-morpholin-4-yl-5-(1H-1,2,4-triazol-5-yl)thiophene-3-carbonitrile

Appearance: Solid

Formulation: N/A

CAS Number: 1276553-09-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₃FN₆OS

Molecular Weight: 380.4

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A novel potent and selective PI3K inhibitor

MDL Number: N/A

PubChem CID: 51033720

SMILES: C1COCCN1C2=C(C(=C(S2)C3=NC=NN3)C4=C(C=C(C=C4)C#N)F)C#N

InChi: InChI=1S/C18H13FN6OS/c19-14-7-11(8-20)1-2-12(14)15-13(9-21)18(25-3-5-26-6-4-25)27-16(15)17-22-10-23-24-17/h1-2,7,10H,3-6H2,(H,22,23,24)

InChi Key: MUENOTXSRZEFJV-UHFFFAOYSA-N