Description
PF74 is a HIV-1 inhibitor that targets HIV capsid protein. PF74 binds specifically to HIV-1 particles and triggers premature HIV-1 uncoating in target cells. PF74 acts at an early stage of HIV-1 infection and inhibits reverse transcription in target cells.
PF74 is a HIV-1 inhibitor that targets HIV capsid protein. PF74 binds specifically to HIV-1 particles and triggers premature HIV-1 uncoating in target cells. PF74 acts at an early stage of HIV-1 infection and inhibits reverse transcription in target cells.
Alternate Name/Synonyms: PF-3450074, PF-74, 2-Methyl-N-[(1S)-2-(methylphenylamino)-2-oxo-1-(phenylmethyl)ethyl]- 1H-indole-3-acetamide
Appearance: Crystalline solid
Formulation:
CAS Number: 1352879-65-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₇H₂₇N₃O₂
Molecular Weight: 525.53
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: 5 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A HIV-1 inhibitor
MDL Number:
PubChem CID: 49800090
SMILES: CC1=C(C2=CC=CC=C2N1)CC(=O)NC(CC3=CC=CC=C3)C(=O)N(C)C4=CC=CC=C4
InChi: InChI=1S/C27H27N3O2/c1-19-23(22-15-9-10-16-24(22)28-19)18-26(31)29-25(17-20-11-5-3-6-12-20)27(32)30(2)21-13-7-4-8-14-21/h3-16,25,28H,17-18H2,1-2H3,(H,29,31)/t25-/m0/s1
InChi Key: ACDFWSNAQWFRRF-VWLOTQADSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |