PFN1 Antibody (C-term) [APR33241G]

PFN1 Antibody (C-term) [APR33241G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PFN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-120 amino acids from the C-terminal region of human PFN1.

Cellular Localisation: Cytoplasm, cytoskeleton.

Molecular Weight: 15054

Clone: Polyclonal

Gene Name: PFN1

Gene ID: 5216

Function: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

Summary: Tissue Location: Expressed in epididymis (at protein level) .

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000 WB--1:8000

Synonyms: Profilin-1, Epididymis tissue protein Li 184a, Profilin I, PFN1