PHB Antibody [APR09107G]

PHB Antibody [APR09107G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H, M, Rat

Specificity: This antibody is generated from a mice immunized with a recombinant protein between 1-205 amino acids from human.

Cellular Localisation: Mitochondrion inner membrane. Nucleus. Cytoplasm. Cell membrane

Molecular Weight: 29804

Clone: Monoclonal

Gene Name: PHB (HGNC:8912)

Gene ID: 5245

Function: Protein with pleiotropic attributes mediated in a cell- compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus (PubMed:11302691, PubMed:20959514, PubMed:28017329, PubMed:31522117) . Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner (By similarity) . Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells (By similarity) .

Summary: Tissue Location: Widely expressed in different tissues.

Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, IHC-P

Dilution: IHC-P--1:100~500 WB--1:1000

Synonyms: Prohibitin, PHB