PHB Antibody (C-term E194) [APR31979G]

PHB Antibody (C-term E194) [APR31979G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the C-terminal region of human PHB.

Cellular Localisation: Mitochondrion inner membrane. Nucleus. Cytoplasm. Cell membrane

Molecular Weight: 29804

Clone: Polyclonal

Gene Name: PHB (HGNC:8912)

Gene ID: 5245

Function: Protein with pleiotropic attributes mediated in a cell- compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus (PubMed:11302691, PubMed:20959514, PubMed:28017329, PubMed:31522117) . Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner (By similarity) . Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells (By similarity) .

Summary: Tissue Location: Widely expressed in different tissues.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Prohibitin, PHB