Description
PhiKan083 is a p53 stabilizing agent; preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan083 slows rate of thermal denaturation of p53-Y220C.
PhiKan083 is a p53 stabilizing agent; preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan083 slows rate of thermal denaturation of p53-Y220C.
Alternate Name/Synonyms: 9-Ethyl-N-methyl-9H-carbazole-3-methanamine hydrochloride
Appearance: White solid
Formulation: N/A
CAS Number: 880813-36-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₈N₂.HCl
Molecular Weight: 274.79
Cell-Permeable?: Yes
Purity: ≥98%
Solubilities: DMSO (>20 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A p53 stabilizing agent
MDL Number: N/A
PubChem CID: 16255105
SMILES: CCN1C2=C(C=C(C=C2)CNC)C3=CC=CC=C31.Cl
InChi: InChI=1S/C16H18N2.ClH/c1-3-18-15-7-5-4-6-13(15)14-10-12(11-17-2)8-9-16(14)18;/h4-10,17H,3,11H2,1-2H3;1H
InChi Key: IXWVUPURFWFRNE-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |