LBD
Phospho-AMOT (S1041) Antibody [APR05240G]
- SKU:
- LBD-APR05240G
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- Usually ships in 5 working days
Description
Phospho-AMOT (S1041) Antibody [APR05240G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This AMOT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1041 of human AMOT.
Cellular Localisation: Cell junction, tight junction. Note=Localized on the cell surface. May act as a transmembrane protein
Molecular Weight: 118085
Clone: Polyclonal
Gene Name: AMOT
Gene ID: 154796
Function: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
Summary: Tissue Location: Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: DB
Dilution: DB--1:500
Synonyms: Angiomotin, AMOT, KIAA1071