LBD
Phospho-CDKN2A (S8) Antibody [APR05289G]
- SKU:
- LBD-APR05289G
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Description
Phospho-CDKN2A (S8) Antibody [APR05289G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CDKN2A Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S8 of human CDKN2A.
Cellular Localisation: Cytoplasm. Nucleus
Molecular Weight: 16533
Clone: Polyclonal
Gene Name: CDKN2A (HGNC:1787)
Gene ID: 1029
Function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Summary: Tissue Location: Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: DB
Dilution: DB--1:500
Synonyms: Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3, Cyclin-dependent kinase 4 inhibitor A, CDK4I, Multiple tumor suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2A, CDKN2, MTS1