Phospho Histone H3 (Ser10) Antibody | A1943

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intron-less and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack poly A tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

A1943 | Phospho Histone H3 (Ser10) Antibody DataSheet

Antibody Target: Phospho Histone H3 (Ser10)

Target Alternative Name: HIST3H3; H3.4; H3/g; H3FT; H3t; histone H3.1t

Tag Line: Affinity purified rabbit polyclonal antibody to detect phosphorylation of Histone H3 at Ser10 in human samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Human

Immunogen Sequence: A synthetic phosphorylated peptide around Ser10 of human Histone H3

Accession #: Q16695

Gene ID: 8290

Appearance: Liquid

Form: Liquid

Concentration:

Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purified

Application: Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:2000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False