Phospho-IKKα/β(S176/180) Polyclonal Antibody | E-AB-68178

Phospho-IKKα/β(S176/180) Polyclonal Antibody | E-AB-68178 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: CHUK, IKBKA, IKBKB, IKK-alpha, IKK-beta, IKK1, IKKA, IKKB, NFKBIKA, NFKBIKB, TCF16, IKK alpha, IKK beta

Application: WB

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A synthetic phosphorylated peptide around S176 of human IKK-alpha (NP_001269.3).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 84 kDa/29 kDa/79 kDa/85 kDa/86 kDa

Molecular Weight(Observed): 85 kDa