Phospho-NF-kB p65(S536) Polyclonal Antibody | E-AB-68093

Phospho-NF-kB p65(S536) Polyclonal Antibody | E-AB-68093 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: NFKB3, p65, NF-kB p65, RELA, CMCU

Application: WB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Neuroscience, Signal Transduction

Background: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A phospho specific peptide corresponding to residues surrounding S536 of human NF-kB p65

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 58 kDa/59 kDa/60 kDa

Molecular Weight(Observed): 60 kDa/70 kDa