Phospho-NFKBIA(S32) Polyclonal Antibody | E-AB-68197

Phospho-NFKBIA(S32) Polyclonal Antibody | E-AB-68197 | Gentaur UK, US & Europe Distribution

Type: Phosphorylated antibody

Synonyms: IKBA, MAD-3, NFKBI, IKB alpha, NFKBIA, EDAID2

Application: WB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signaling transduction

Background: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A synthetic phosphorylated peptide around S32 of human NFKBIA (NP_065390.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 35 kDa

Molecular Weight(Observed): 39 kDa/41 kDa