LBD
Phospho-RGS19 (S24) Antibody [APR09245G]
- SKU:
- LBD-APR09245G
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Description
Phospho-RGS19 (S24) Antibody [APR09245G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This RGS19 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S24 of human RGS19.
Cellular Localisation: Membrane; Lipid-anchor.
Molecular Weight: 24636
Clone: Polyclonal
Gene Name: RGS19
Gene ID: 10287
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G (i) a3 > G (i) a1 > G (o) a >> G (z) a/G (i) a2. Activity on G (z) -alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Summary: Tissue Location: Highest expression in lung. Placenta, liver and heart also express high levels of GAIP
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein A affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: DB
Dilution: DB--1:500
Synonyms: Regulator of G-protein signaling 19, RGS19, G-alpha-interacting protein, GAIP, RGS19, GAIP, GNAI3IP