PHT-427 | 2465

A potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor. PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity.

PHT-427 is a potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor.

2465 | PHT-427 DataSheet

Alternate Name/Synonyms: 4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1191951-57-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₃₁N₃O₃S₂

Molecular Weight: 409.61

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (> 80 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent Akt and PDPK1 inhibitor

MDL Number: N/A

PubChem CID: 44240850

SMILES: CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2

InChi: InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)

InChi Key: BYWWNRBKPCPJMG-UHFFFAOYSA-N