Phyllanthin | B2777

Phyllanthin is a major bioactive lignan found in many Phyllanthus species. It displays various biochemical and pharmacological properties especially on its hepatoprotective effects. It scavenges DPPH radicals with an IC50 value of 7.4 µM and, at 30 µM, has been shown to alleviate carbon tetrachloride-induced lipid peroxidation and cytotoxicity in a human hepatoma HepG2 cell line.

Phyllanthin is a major bioactive lignan found in many Phyllanthus species. It displays various biochemical and pharmacological properties especially on its hepatoprotective effects.It scavenges DPPH radicals with an IC50 value of 7.4 µM and, at 30 µM, has been shown to alleviate carbon tetrachloride-induced lipid peroxidation and cytotoxicity in a human hepatoma HepG2 cell line.

B2777 | Phyllanthin DataSheet

Alternate Name/Synonyms: (2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutane,NSC-619043

Appearance: Crystalline solid

Formulation:

CAS Number: 10351-88-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₃₄O₆

Molecular Weight: 418.52

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: ~10 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A major bioactive lignan found in many Phyllanthus species

MDL Number: MFCD17166965

PubChem CID: 358901

SMILES: COC1=C(OC)C=C(C[C@]([C@@](CC2=CC=C(OC)C(OC)=C2)([H])COC)([H])COC)C=C1

InChi: InChI=1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1 Computed by InChI 1.0.5 (PubChem release 2019.06.18)

InChi Key: KFLQGJQSLUYUBF-WOJBJXKFSA-N