PI3 Antibody | 19-664

PI3 Antibody | 19-664 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-117 of human PI3 (NP_002629.1) .

Research Area: Cancer, Cell Cycle, Immunology, Innate Immunity

Tested Application: WB, IHC

Application: WB: 1:500 - 1:2000
IHC: 1:100 - 1:200

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: HepG2

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 12kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: PI3, ESI, MGC13613, SKALP, WAP3, WFDC14, cementoin

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.