PI3KC2B Antibody (N-term) [AMM07180G]

PI3KC2B Antibody (N-term) [AMM07180G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PI3KC2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-150 amino acids from the N-terminal region of human PI3KC2B.

Cellular Localisation: Microsome. Cell membrane. Cytoplasm, cytosol Nucleus. Endoplasmic reticulum. Note=Found mostly in the microsome, but also in the plasma membrane and cytosol. Nuclear in testis

Molecular Weight: 184768

Clone: Polyclonal

Gene Name: PIK3C2B

Gene ID: 5287

Function: Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns (PubMed:10805725, PubMed:9830063, PubMed:11533253) . Does not phosphorylate PtdIns (4, 5) P2 (PubMed:9830063) . May be involved in EGF and PDGF signaling cascades (PubMed:10805725) .

Summary: Tissue Location: Expressed in columnar and transitional epithelia, mononuclear cells, and ganglion cells (at protein level) . Widely expressed, with highest levels in thymus and placenta and lowest in peripheral blood, skeletal muscle and kidney

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P

Dilution: IHC-P--1:100~500

Synonyms: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, PI3K-C2-beta, PtdIns-3-kinase C2 subunit beta, C2-PI3K, Phosphoinositide 3-kinase-C2-beta, PIK3C2B