PI4KA Antibody (Center) [AMM07186G]

PI4KA Antibody (Center) [AMM07186G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This PI4KA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1460-1490 amino acids of mouse PI4KA.

Cellular Localisation: Cytoplasm. Cell membrane Note=Localization to the plasma membrane is mediated by the PI4K complex and association with EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and FAM126 (FAM126A or FAM126B) (PubMed:23229899) . Localization to the plasma membrane is regulated by TMEM150A (PubMed:25608530)

Molecular Weight: 236830

Clone: Polyclonal

Gene Name: PI4KA

Gene ID: 5297

Function: Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1, 4, 5, - trisphosphate.

Summary: Tissue Location: Expressed ubiquitously. Highest levels in placenta and brain. Little or no expression in lung, liver, pancreas, testis or leukocytes.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Phosphatidylinositol 4-kinase alpha, PI4-kinase alpha, PI4K-alpha, PtdIns-4-kinase alpha, 2.7.1.67, PI4KA, PIK4, PIK4CA