PIAS3 Polyclonal Antibody | E-AB-17823

PIAS3 Polyclonal Antibody | E-AB-17823 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: E3 SUMO protein ligase PIAS 3, E3 SUMO protein ligase PIAS3, E3 SUMO-protein ligase PIAS3, FLJ14651, OTTHUMP00000015586, OTTHUMP00000015587, PIAS 3, Pias3, PIAS3 protein, PIAS3, Protein inhibitor of activated STAT 3, Protein inhibitor of activated STAT protein 3, Protein inhibitor of activated STAT3, Zinc finger MIZ type containing 5, ZMIZ 5, ZMIZ5

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Background: This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.

Concentration: 1.1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human PIAS3

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A