Pifithrin-ɑ | 1554

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53-dependent transcriptional activation and apoptosis.

Pifithrin-alpha is a chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Reversibly blocks p53-dependent transcriptional activation and apoptosis.

1554 | Pifithrin-ɑ DataSheet

Alternate Name/Synonyms: PFT-α, 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide

Appearance: White solid

Formulation: N/A

CAS Number: 63208-82-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₈N₂OS . HBr

Molecular Weight: 367.3

Cell-Permeable?: Yes

Purity: ≥99%

Solubilities: DMSO ( 20 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A p53 inhibitor

MDL Number: MFCD00417851

PubChem CID: 9929138

SMILES: CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br

InChi: InChI=1S/C16H18N2OS.BrH/c1-11-6-8-12(9-7-11)14(19)10-18-13-4-2-3-5-15(13)20-16(18)17;/h6-9,17H,2-5,10H2,1H3;1H

InChi Key: HAGVCKULCLQGRF-UHFFFAOYSA-N