Pifithrin-α, Cyclic, hydrobromide | 2270

A cyclic analog of the p53 inhibitor Pifithrin-α (Cat.No.1554-10). Sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis.

Cyclic Pifithrin-α is a cyclic analog of the p53 inhibitor Pifithrin-α (Cat.No.1554-10). Sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis.

2270 | Pifithrin-α, Cyclic, hydrobromide DataSheet

Alternate Name/Synonyms: 5,6,7,8-Tetrahydro-2-(4-methylpheny­l)-imidazo[2,1-b]benzothiazole hydrobromide; QB102

Appearance: White solid

Formulation: N/A

CAS Number: 511296-88-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₆N₂S ∙ HBr

Molecular Weight: 349.29

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (100 mM) or EtOH (10 mM)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A p53 inhibitor

MDL Number: MFCD02683960

PubChem CID: 11515812

SMILES: CC1=CC=C(C=C1)C2=CN3C4=C(CCCC4)SC3=N2.Br

InChi: InChI=1S/C16H16N2S.BrH/c1-11-6-8-12(9-7-11)13-10-18-14-4-2-3-5-15(14)19-16(18)17-13;/h6-10H,2-5H2,1H3;1H

InChi Key: SGNCOAOESGSEOP-UHFFFAOYSA-N