PIK3C3 Antibody | 7891

PIK3C3 Antibody | 7891 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Pig: (100%)

Immunogen: PIK3C3 antibody was raised against an 18 amino acid peptide near the amino terminus of human PIK3C3.
The immunogen is located within amino acids 130 - 180 of PIK3C3.

Research Area: Autophagy

Tested Application: E, WB

Application: PIK3C3 antibody can be used for detection of PIK3C3 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Specificiy: PIK3C3 antibody is human, mouse and rat reactive.

Positive Control 1: Cat. No. 1408 - Mouse Small Intestine Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 91, 98 kDa
Observed: 98 kDa

Validation: N/A

Isoform: N/A

Purification: PIK3C3 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PIK3C3 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: PIK3C3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: PIK3C3 Antibody: VPS34, hVps34, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, PI3-kinase type 3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit) , also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase class III) , is a member of the PI3/PI4-kinase family (1) . It is a catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate and ubiquitously expressed with a highest expression in skeletal muscle (1, 2) . PIK3C3 is involved in the endosome to lysosome transport and plays important roles in intracellular membrane trafficking and autophagy (3-5) .