BW
PIK3R5 monoclonal Antibody | MB64505
- SKU:
- BW-MB64505
- Availability:
- Usually ships in 5 working days
Description
PIK3R5 monoclonal Antibody | MB64505 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat, Dog
Application: IF, IHC, WB
Application Range: WB 1:100~1000, IHC 1:150, IF 1:100
Background: Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: phosphoinositide-3-kinase regulatory subunit 5
Molecular Weight: 97.2 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: F730038I15Rik; FOAP-2; p101; P101-PI3K
Immunogen: Full length human recombinant protein of human PIK3R5 (NP_055123) produced in HEK293T cell.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A