Pimozide | 1887

Cell-permeable. An antipsychotic drug and D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor. A Stat5 inhibitor; decreases Stat5 tyrosine phosphorylation, but does not affect Bcr-Abl or other tyrosine kinases.

Pimozide is an antipsychotic drug and D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor. A Stat5 inhibitor; decreases Stat5 tyrosine phosphorylation, but does not affect Bcr-Abl or other tyrosine kinases.

1887 | Pimozide DataSheet

Alternate Name/Synonyms: 1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one

Appearance: White solid

Formulation: N/A

CAS Number: 2062-78-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₂₉F₂N₃O

Molecular Weight: 461.55

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (100 mM)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A Stat5 inhibitor

MDL Number: MFCD00055081

PubChem CID: 16362

SMILES: C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F

InChi: InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4- 3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14, 24-25H,3-4,15-19H2,(H,31,34)

InChi Key: YVUQSNJEYSNKRX-UHFFFAOYSA-N