PIP4K2C Antibody (N-term) [AMM07196G]

PIP4K2C Antibody (N-term) [AMM07196G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M, Rat

Specificity: This PIP4K2C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 23-57amino acids from the N-terminal region of human PIP4K2C.

Cellular Localisation: Endoplasmic reticulum {ECO:0000250|UniProtKB:O88370}. Cytoplasm {ECO:0000250|UniProtKB:O88370}

Molecular Weight: 47300

Clone: Polyclonal

Gene Name: PIP4K2C (HGNC:23786)

Gene ID: 79837

Function: Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns (4, 5) P2 synthesis and insulin- dependent conversion to PtdIns (3, 4, 5) P3 (PubMed:31091439) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, Phosphatidylinositol 5-phosphate 4-kinase type II gamma, PI (5) P 4-kinase type II gamma, PIP4KII-gamma, PIP4K2C, PIP5K2C