Pirarubicin | B2216

Pirarubicin is an analog of doxorubicin, that acts as an antineoplastic drug. Pirarubicin is transported into cells via a sodium-dependent nucleoside transporter. It is used to intercalate DNA and inhibit the activity of topoisomerase II and induce DNA crosslinking.

Pirarubicin is an analog of doxorubicin, that acts as an antineoplastic drug. Pirarubicin is transported into cells via a sodium-dependent nucleoside transporter. It is used to intercalate DNA and inhibit the activity of topoisomerase II and induce DNA crosslinking.

B2216 | Pirarubicin DataSheet

Alternate Name/Synonyms: (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-6-methyl-5-(((S)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

Appearance: Red solid

Formulation: N/A

CAS Number: 72496-41-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₃₇NO₁₂

Molecular Weight: 627.64

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: EtOH (~25 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An anticancer drug

MDL Number: MFCD00869742

PubChem CID: 636397

SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6

InChi: InChI=1S/C32H37NO12/c1-14-31(45-21-8-3-4-9-42-21)17(33)10-22(43-14)44-19-12-32(40,20(35)13-34)11-16-24(19)30(39)26-25(28(16)37)27(36)15-6-5-7-18(41-2)23(15)29(26)38/h5-7,14,17,19,21-22,31,34,37,39-40H,3-4,8-13,33H2,1-2H3/t14-,17-,19-,21-,22-,31+,32-/m0/s1

InChi Key: KMSKQZKKOZQFFG-HSUXVGOQSA-N