Pitx1 (E130) polyclonal Antibody | BS2482

Pitx1 (E130) polyclonal Antibody | BS2482 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Pitx1 and Pitx2 are highly homologous, bicoid-related transcription factors. Pitx1 is a bicoid-related homeodomain factor that exhibits preferential expression in the hindlimb, as well as expression in the developing anterior pituitary gland and first branchial arch. Deletion of the Pitx1 locus results in decreased distal expression of the hindlimb-specific marker, the T-box factor (Tbx4) . Pitx1 may modulate morphogenesis, growth and patterning of a specific hindlimb region, and serves as a component of the variables that influence morphological and growth distinctions in forelimb and hindlimb identity.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Pitx1 (E130) polyclonal Antibody detects endogenous levels of Pitx1 protein.

Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Hindlimb-expressed homeobox protein backfoot; PITX1; BFT. POTX. PTX1

Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human Pitx1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: