PK 11195 | 2054

Cell-permeable. A Selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays anticancer activity.

PK11195 is a selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays anticancer activity.

2054 | PK 11195 DataSheet

Alternate Name/Synonyms: 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 85532-75-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₁ClN₂O

Molecular Weight: 352.86

Cell-Permeable?: Yes

Purity: ≥98% by NMR

Solubilities: DMSO or EtOH

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A Selective peripheral benzodiazepine antagonist.

MDL Number: MFCD00069334

PubChem CID: 1345

SMILES: CCC(C)N(C)C(=O)C1=CC2=CC=CC=C2C(=N1)C3=CC=CC=C3Cl

InChi: InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23- 19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3

InChi Key: RAVIZVQZGXBOQO-UHFFFAOYSA-N