Description
PKLR Polyclonal Antibody | E-AB-67386 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: PKLR, PK1, PKL, PKR, PKRL, RPK
Application: IHC
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal Transduction
Background: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human PKLR (NP_000289.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A