PKM2 (1F2) monoclonal Antibody | MB0189

PKM2 (1F2) monoclonal Antibody | MB0189 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Mouse,Monkey

Application: WB IF

Application Range: WB: 1:1000 IF: 1:100~500

Background: The PKM2 (pyruvate kinase, muscle) gene encodes the M1- and M2-type isoenzymes through alternative splicing events. Both M1- and M2-type isoforms exists as tetramers and are stimulated by fructose 1,6-bisphosphate. In addition, both isoforms exhibit thyroid hormone binding activity and may be referred to as CTHBP (cytosolic thyroid hormone-binding protein) or THBP1.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of PKM2 and does not cross-react with related proteins.

Molecular Weight: Predicted band size:58KDa Observed band size:58KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CTHBP; Cytosolic thyroid hormone binding protein; Cytosolic thyroid hormone-binding protein; KPYM; MGC3932; OIP 3; OIP-3; Oip3; OIP3; OPA interacting protein 3; Opa-interacting protein 3; p58; PK Muscle type; PK; muscle type; PK2; Pk3; PKM; PKM2; PYKM; Pyruvate kinase 2/3; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; TCB; THBP1; Thyroid hormone binding protein 1; Thyroid hormone binding protein cytosolic; Thyroid hormone

Immunogen: Purified recombinant human PKM2 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: TGFβ Smad signaling,