PLA2G4D Antibody (C-Term) [AMR09320G]

PLA2G4D Antibody (C-Term) [AMR09320G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This PLA2G4D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 754-786 amino acids from human PLA2G4D.

Cellular Localisation: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q50L43}. Membrane {ECO:0000250|UniProtKB:Q50L43}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q50L43}; Cytoplasmic side {ECO:0000250|UniProtKB:Q50L43}. Note=Translocates to perinuclear membranes that may correspond to endoplasmic reticulum or Golgi in a calcium-dependent fashion. {ECO:0000250|UniProtKB:Q50L43}

Molecular Weight: 91952

Clone: Polyclonal

Gene Name: PLA2G4D (HGNC:30038)

Gene ID: 283748

Function: Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position (PubMed:14709560) . Has a preference for linoleic acid at the sn-2 position (PubMed:14709560) .

Summary: Tissue Location: Expressed in stratified squamous epithelia, such as those in skin and cervix, but not in other tissues (PubMed:14709560) Strongly expressed in the upper spinous layer of the psoriatic epidermis, expressed weakly and discontinuously in atopic dermatitis and mycosis fungoides, and not detected in the epidermis of normal skin (PubMed:14709560) .

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Cytosolic phospholipase A2 delta, cPLA2-delta, Phospholipase A2 group IVD, PLA2G4D