LBD
PLA2G4F Antibody (Center) [AMR09322G]
- SKU:
- LBD-AMR09322G
- Availability:
- Usually ships in 5 working days
Description
PLA2G4F Antibody (Center) [AMR09322G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This PLA2G4F antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 289-331 amino acids from the Central region of human PLA2G4F.
Cellular Localisation: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q50L41}. Cell membrane {ECO:0000250|UniProtKB:Q50L41}; Peripheral membrane protein. Mitochondrion
Molecular Weight: 95082
Clone: Polyclonal
Gene Name: PLA2G4F
Gene ID: 255189
Function: Has calcium-dependent phospholipase and lysophospholipase activities with a potential role in membrane lipid remodeling and biosynthesis of lipid mediators (PubMed:29158256) . Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) (PubMed:29158256) . Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis (PubMed:29158256) . In myocardial mitochondria, plays a major role in arachidonate release that is metabolically channeled to the formation of cardioprotective eicosanoids, epoxyeicosatrienoates (EETs) (PubMed:29158256) .
Summary: Tissue Location: Expressed in myocardium (at protein level) .
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Cytosolic phospholipase A2 zeta, cPLA2-zeta, 3.1.1.4, Phospholipase A2 group IVF, PLA2G4F