LBD
PLCD3 Antibody (N-term) [AMM07236G]
- SKU:
- LBD-AMM07236G
- Availability:
- Usually ships in 5 working days
Description
PLCD3 Antibody (N-term) [AMM07236G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M
Specificity: This PLCD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human PLCD3.
Cellular Localisation: Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow. Note=Localizes at the cleavage furrow during cytokinesis.
Molecular Weight: 89258
Clone: Polyclonal
Gene Name: PLCD3 (HGNC:9061)
Gene ID: 113026
Function: Hydrolyzes the phosphatidylinositol 4, 5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3) . DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca (2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow (PubMed:10336610) . Regulates neurite outgrowth through the inhibition of RhoA/Rho kinase signaling (By similarity) .
Summary: Tissue Location: Present in corneal epithelial cells (at protein level) .
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase delta-3, Phosphoinositide phospholipase C-delta-3, Phospholipase C-delta-3, PLC-delta-3, PLCD3, KIAA1964