PLCgamma2 (phospho Tyr753) Antibody | 79-462

PLCgamma2 (phospho Tyr753) Antibody | 79-462 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: PLCgamma2 (Phospho-Tyr753) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 753 (S-L-Y (p) -D-V) derived from Human PLCγ2.

Research Area: Phospho-Specific, Neuroscience

Tested Application: WB, IF

Application: Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Specificiy: This antibody detects endogenous level of PLCγ2 only when phosphorylated at tyrosine 753.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 150 kDa

Validation: N/A

Isoform: N/A

Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration: 1 mg/mL

Storage Condition: Store antibody at -20˚C for up to one year.

Alternate Name: FCAS3, APLAID, PLC-IV, PLC-gamma-2, MEK6, MKK6, PRKMK6, SKK3, PLC-gamma2, Phospholipase C-gamma-2

User Note: N/A

BACKGROUND: The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.